Jul 2026· International Journal of Polymer and Textile Engineering· 0 citations· 49 references
TL;DR
The results demonstrated that AgNPs-loaded mats exhibited the highest inhibition zones, followed by neem-loaded mats, while chitosan showed comparatively lower activity, which highlights the comparative effectiveness of incorporating different antibacterial agents into PVA-CMC polymer-based nanofibers.
Abstract
Electrospinning has emerged as a versatile and efficient technique for producing antibacterial nanofibrous mats by enabling the incorporation of various bioactive agents into polymeric fiber systems. In this study, nanofibrous mats based on poly(vinyl alcohol) (PVA) and Carboxymethyl Cellulose (CMC) polymers were successfully fabricated with the inclusion of three different Antibacterial Agents, Namely Chitosan, Silver Nanoparticles (AgNPs), and ethanolic extract of neem (Azadirachta indica) leaf. The electrospinning solutions were prepared using a fixed volumetric ratio (PVA:CMC:antibacterial additive) in order to establish a comparative evaluation of structural and antibacterial performance under identical conditions. Synthesized AgNPs exhibited a narrower particle size distribution, confirming uniform nanoparticle formation. SEM images revealed the formation of continuous, randomly oriented nanofibrous networks. FTIR spectroscopy confirmed the presence of characteristic functional groups of the antibacterial agents without significant alteration of the base polymeric structures. The agar disk diffusion method was employed to evaluate antibacterial activity against Escherichia coli and Staphylococcus aureus, and the results demonstrated that AgNPs-loaded mats exhibited the highest inhibition zones, followed by neem-loaded mats, while chitosan showed comparatively lower activity. Overall, this study highlights the comparative effectiveness of incorporating different antibacterial agents into PVA-CMC polymer-based nanofibers.
Electrospun poly-based fibers functionalized with silver and gold nanoparticles demonstrated an excellent balance of safety, cytocompatibility, and antibacterial performance, making them promising candidates for biomedical applications that require both inflammation control and antimicrobial protection.
Antónia Kurillová, Saverio Caporalini, Bahareh Azimi et al.· Frontiers in Bioengineering...· 0 citations
This PCL-CS/6% Fe2O3 hybrid compound offers potential as an alternative to engineered medical tissues for antimicrobial applications, allowing for the production of materials with optical and electrical properties, as well as antioxidant, antibacterial, and antifungal effects.
Maher Hassan Rasheed, Mohsin K. Al-khaykanee, Q. Kadhim et al.· Polymer Bulletin· 0 citations
This study presents an eco-friendly strategy for synthesizing copper oxide nanoparticles (CuO NPs) using the brown marine algae Dictyota as a biogenic source. The ultrasonic-assisted extraction of algal bioactives facilitated efficient nanoparticle formation, which was confirmed by UV–Vis, Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Dynamic light scattering (DLS), and zeta potential analyses. The synthesized CuO NPs were incorporated into a starch/polyvinyl alcohol (PVA) matrix to fabricate electrospun nanofibrous scaffolds with enhanced structural integrity and biological functionality. Physicochemical characterization revealed uniform fiber morphology, strong thermal stability, and successful nanoparticle integration. The antimicrobial potential of the scaffolds was evaluated against pathogenic bacterial and fungal strains, demonstrating significant inhibitory effects. This work highlights the synergistic benefits of green synthesis and polymeric nanofiber technology, proposing a sustainable and biocompatible platform for antimicrobial applications. Overall, the study contributes to the advancement of marine-derived nanomaterials and their potential in biomedical and environmental fields.
Elsa Sharon Emarald Ruban, Harish Manoharan, Nishandhini Marimuthu et al.· Genetics and Molecular Resea...· 0 citations
This study presents the development of a sustainable antimicrobial nanofibrous system by incorporating biosynthesized CuO NPs (copper oxide nanoparticles) into electrospun polymeric matrices. Aqueous extracts of the brown marine alga Sargassum ilicifolium were utilized for ultrasonic-assisted extraction, enabling an environmentally friendly nanoparticle synthesis process. The resulting CuO NPs exhibited nanoscale dimensions (~108 nm), monoclinic crystallinity, and moderate dispersion stability (−18.3 mV), as confirmed through UV–Vis, FTIR, XRD, SEM, TGA, and DLS analyses. These nanoparticles were homogeneously embedded within starch/PVA solutions and electrospun to produce uniform, bead-free fibers with a porous architecture. Antimicrobial performance was evaluated against pathogenic microorganisms. The nanoscaffolds (50 µg/mL) demonstrated superior inhibitory activity compared to both the algal extract and standalone nanoparticles, with maximum zones observed for E. coli (31±0.16 mm) and Penicillium sp. (27±0.23 mm). The fabricated polymeric nanoscaffolds promoting effective microbial contact and sustained ion release, highlighting their potential as eco-friendly antimicrobial biomaterials.
Rajendraprasad Kunamalla, Mani Panagal, C. Palanisamy· Genetics and Molecular Resea...· 0 citations
Sustainable packaging plays a critical role in addressing the severe environmental pollution caused by synthetic polymers. In this study, pectin-incorporated polyvinyl alcohol (PVA) nanofibers containing Perovskia abrotanoides essential oil (EO) and its nanoemulsion form (NEO) were successfully optimized and fabricated using electrospinning. Physicochemical properties were characterized using SEM, FTIR, DSC, XRD, and zeta potential analysis. Optimal electrospinning parameters were achieved with 8% PVA and 2% pectin (80:20), a feed rate of 1 mL/h, and an applied voltage of 18.0 kV, yielding uniform, bead-free nanofibers. EO and NEO were incorporated at concentrations of 0.5 MIC, 1 MIC, and 2 MIC to assess their antioxidant and antibacterial performance. SEM analysis revealed that 2 MIC EO and 0.5 MIC NEO produced smoother nanofibers with mean diameters of 898 ± 240 nm and 755 ± 148 nm, respectively, along with enhanced antibacterial efficacy against seven foodborne pathogens. Compared with EO-loaded systems, NEO-loaded nanofibers exhibited higher absolute zeta potential values ( -5.9 mV for 2NEO) and superior stability mechanical properties. Overall, this study suggests that PVA/pectin nanofibers containing Perovskia abrotanoides NEO are promising sustainable multifunctional packaging material.
Samaneh Tabibian, Maryam Hashemi, P. Innocenzi et al.· Scientific Reports· 0 citations
Antibacterial dressings are crucial for the prevention and treatment of wound infections. Silver nanoparticles (AgNPs), known for their high-efficiency and broad-spectrum antibacterial properties, are commonly used in such dressings. However, silver nanoparticles are easily agglomerated under light and environmental media, causing unstable silver ion release in these dressings. This restricts long-term antibacterial effectiveness and fails to meet clinical needs. To solve this problem, negatively charged cellulose nanocrystals (CNC) were used to enhance the dispersion of silver nanoparticles. Meanwhile, tannic acid (TA) was employed to reduce silver ions, while enhancing the complexation between CNC and silver nanoparticles, effectively alleviating the agglomeration of silver nanoparticles. Subsequently, these silver nanoparticles combined with CNC and TA were integrated into a PP (PVA-PEG) hydrogel matrix. Experimental results show that the hydrogel dressing exhibits excellent performance. Silver nanoparticle dispersion is greatly improved, and Ag+ release becomes sustained. The antibacterial rate against common pathogens is above 99%, and a high antibacterial rate is still maintained after one week of light exposure. In addition, the physical properties of the PP hydrogel are optimized. Our findings provide a new strategy for antibacterial dressings, aiming to enhance the therapeutic effect of wound dressings, offer a novel preparation method for nano‑silver antibacterial materials, and promote the development of green medical materials.
Junreng Liu, Wenxuan Wang, Yimin Shi et al.· International Journal of Bio...· 0 citations
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