Sep 2026· The Professional Medical Journal· 0 citations· 30 references
TL;DR
Nearly one in four ischemic stroke patients in this cohort had AF, with older age and metabolic risk factors such as diabetes and obesity showing strong associations, which underscore the importance of targeted cardiac screening to guide anticoagulation and improve secondary stroke prevention.
Abstract
Objective: To determine the frequency of atrial fibrillation (AF) and its associated clinical factors among patients presenting with acute ischemic stroke at a tertiary care hospital. Study Design: Cross-sectional Observational study. Setting: Ayub Medical Teaching Institute, Abbottabad, a Tertiary Care Hospital. Period: January 20, 2026, to April 22, 2026. Methods: A total of 167 consecutive adults aged ≥18 years with CT- or MRI-confirmed acute ischemic stroke presenting within 7 days of symptom onset were enrolled. Patients with hemorrhagic stroke, transient ischemic attack, non-vascular causes, incomplete records, or those who declined consent were excluded. AF was identified through documented medical history and admission 12-lead electrocardiography. Demographic and cardiovascular risk factor data were collected via a structured proforma. Statistical analysis was performed using SPSS version 26, with associations assessed by the Chi-square test. Results: +AF was detected in 38 patients (23%). The overall cohort had a mean age of 65.2 ± 12.4 years, and 58.7% were male. Patients with AF were significantly older (70.1 ± 13.2 vs. 63.8 ± 11.9 years; age >65 years: 68.4% vs. 48.1%, p=0.031). Significant associations with AF were found for diabetes mellitus (52.6% vs. 34.9%, p=0.038) and obesity (34.2% vs. 17.1%, p=0.029). Hypertension was more common in AF patients but did not reach statistical significance (78.9% vs. 63.6%, p=0.082). Sex, smoking, dyslipidemia, and prior stroke showed no significant associations. Conclusion: Nearly one in four ischemic stroke patients in this cohort had AF, with older age and metabolic risk factors such as diabetes and obesity showing strong associations. These findings underscore the importance of targeted cardiac screening to guide anticoagulation and improve secondary stroke prevention.
The study does not establish an altitude-related AF phenotype, the appropriateness of chronic anticoagulation, or prognostic factors for mortality, and Prospective multicentre studies with adjudicated AF, individual altitude exposure, oxygenation and haematologic measures, and longitudinal treatment data are warranted.
Vladimir E. Ullauri-Solórzano, René Antonio Vicuña Mariño, D. Proaño et al.· Medicina· 0 citations
Background: Atrial fibrillation is the most common cardiac arrhythmia and increases the risk of stroke, heart failure, and mortality. NVAF accounts for most AF cases, with treatment focused on anticoagulation and rate or rhythm control. DOAC use has increased globally, but evidence from Bangladesh remains limited. This...
M. Sufian, A. N. M. Monowarul Kadir, Maryam Zahid et al.· Scholars Journal of Applied...· 0 citations
Objective: To evaluate in-hospital outcomes among patients with acute stroke and identify demographic, clinical, and laboratory factors associated with unfavourable outcomes at a tertiary care hospital in Multan, Pakistan.
Methodology: A hospital-based cross-sectional descriptive study was conducted in the Department o...
Muhammad Tahir, Rooh Ul Ameen Khosa, Mahnoor Zainab· Journal of Islamabad Medical...· 0 citations
Descriptive baseline data on AF from a Libyan tertiary center is provided; findings should not be interpreted as population prevalence or as evidence of causal risk factors given the retrospective, single-center, uncontrolled design.
Muna Solyman, Tareq Lehmidi· AlQalam journal of medical a...· 0 citations
Although the presence of AF in patients with ACS was not independently associated with CV mortality, it was independently associated with CV-related hospitalizations despite contemporary treatment strategies, suggesting closer follow-up and more intensive management of ACS patients with AF may be necessary to reduce th...
Murat Gençaslan, Ceyhun Yucel, M. Ardıç et al.· Catheterization and cardiova...· 0 citations
AF in this population was predominantly associated with rheumatic valvular heart disease and structural cardiac abnormalities, particularly left atrial enlargement, particularly left atrial enlargement.
Shashank Narayanappa, Shehla Ashraf, P. C. Paidi et al.· International Journal of Res...· 0 citations
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