Aug 2026· Materials· Vol 19, pp. 3646· 0 citations· 272 references
Medicine
Abstract
Biodegradable metals have emerged as promising alternatives to permanent implants because they provide temporary mechanical support while gradually degrading after tissue healing, eliminating the need for removal surgery. Among the main biodegradable systems, Fe-, Mg-, and Zn-based alloys each offer unique advantages but also face important challenges related to the balance between mechanical performance, corrosion behavior, and biocompatibility. This review summarizes recent advances in the development of these materials, focusing on how alloy design, thermomechanical processing, porous architectures, surface engineering, and additive manufacturing influence their mechanical properties and degradation mechanisms. Special attention is given to the interplay between corrosion and mechanical integrity throughout the implant lifetime, as well as to current strategies for tailoring degradation rates to match tissue healing. Finally, the review discusses the remaining challenges, including the need for standardized testing, improved long-term in vivo validation, and the development of next-generation biodegradable metallic implants with optimized structural, biological, and functional performance.
Biodegradable implants present significant challenges that hinder their widespread clinical application despite their potential benefits. Key issues include inconsistent degradation rates, insufficient mechanical strength, and the risk of inflammatory responses. These challenges must be addressed to enhance the efficac...
V. Greshta, Gulmira Yar-Mukhamedova, A. Imanbayeva et al.· Eurasian physical technical...· 0 citations
The long-term success of orthopedic implants depends not only on their mechanical performance but also on their ability to establish a stable and biologically active interface with surrounding tissues. Despite the widespread clinical use of metallic, ceramic, and polymeric biomaterials, implant failure remains associat...
S. Gavinho, Thacilla Menezes, J. Regadas et al.· Applied Sciences· 0 citations
AISI 316L stainless steel continues to play an important role in orthopedic, dental, and surgical implants because of its favorable balance of mechanical performance, corrosion resistance, manufacturability, and cost-effectiveness. Despite its widespread clinical use, the long-term reliability of this alloy is largely...
Ricardo Luiz Perez Teixeira· Frontiers in Biomaterials Sc...· 0 citations
An in-depth examination of bioactive coatings is offered, categorizing them into three main classes: inorganic, organic, and hybrid with particular attention to their roles in promoting osseointegration, supporting bone regeneration, and reducing implant-associated infection in musculoskeletal and craniofacial applicat...
A. Shanaghi, A. Souri, Majid Naseri et al.· Science in progress· 0 citations
Biodegradable Zn‐based alloys have attracted increasing attention as materials for biomedical implants because they offer moderate degradation rates and favorable biocompatibility compared with Mg‐ and Fe‐based alloys. In physiological environments, their degradation is governed by electrochemical corrosion and typ...
Yi-Xuan Wang, Rui Yang, Huan-Yu Tan et al.· Advanced Functional Material...· 0 citations
The biodegradable Fe‐35Mn alloy has emerged as a promising material for temporary implants due to its excellent mechanical, degradation, magnetic, and biocompatibility properties. Despite these advantages, its in vivo performance can be affected by factors such as friction, wear, and corrosive environments, compromis...
K. B. da Silva, Caio Pascotti Valem, S. Rajan et al.· Materials and Corrosion· 0 citations
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