TL;DR
Adding biomarkers does not improve diagnosis and is over�tted, and serum androgen-hirsutism correlation does not explain hirsutism.
Introduction. Polycystic ovary syndrome (PCOS) is one of the most prevalent endocrine disorders in women of reproductive age; however, its clinical heterogeneity complicates timely stratification of long-term cardiometabolic risk. The lack of a generally accepted algorithm for a differentiated approach at the initial d...
Summary Background Adolescent polyendocrine metabolic ovarian syndrome (PMOS) poses immediate and lifelong risks to women’s health. However, reliable biomarkers for adolescent PMOS remain elusive in current clinical practice. Methods We systematically searched six databases from inception to April 2026, following PRISM...
Background and Objectives: Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine and metabolic disorder characterized by distinct phenotypic presentations. This study aimed to compare androgenic and metabolic characteristics across Rotterdam-defined PCOS phenotypes, with particular emphasis on insulin resistanc...
Compared with controls, women with PCOS had higher body weight, body-mass index, waist circumference, waist circumference, triglyceride levels, insulin resistance-related parameters, triglyceride-glucose (TyG) Index, lipid accumulation product (LAP), and Atherogenic Index of Plasma (AIP), whereas high-density lipoprote...
Polycystic ovary syndrome (PCOS) is a common and highly heterogeneous endocrine–metabolic disorder. The Rotterdam criteria identify four diagnostic phenotypes; however, it remains unclear whether these phenotypes or body mass index (BMI) better predict metabolic risk. The PCOSOUTCOME.net registry collects data from mul...
Ketone supplementation appears to confer significant metabolic and endocrine benefits in women with PCOS, including reductions in BMI, glucose, insulin, LH, and androgens, along with increases in FSH and estrogen.
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