Exploring the antibacterial and antibiofilm potential of 1,8-cineole against Escherichia coli through in vitro, gene expression, and in silico analyses.

Catechins as antibiofilm agents: molecular insights for virtual screening and in vitro biological evaluation

It was concluded that catechin possesses significant antibacterial and antibiofilm potential that be phenotypic response that be phenotypic response.

Antibacterial and Antibiofilm Effects of Resveratrol and Naringin on Multidrug-Resistant Escherichia coli: Associations with Resistance-Related Gene Expression

Background: Multidrug-resistant Escherichia coli represents a significant challenge in antimicrobial therapy because of its ability to acquire resistance mechanisms, form biofilms, and regulate the expression of resistance-associated genes. Plant-derived compounds, including resveratrol and Naringin, have attracted att...

Bactericidal and Antibiofilm Activities of HT-2-1-3, a Vespidae Venom-Derived Antimicrobial Peptide, Against Streptococcus mutans UA159

Background: Dental caries is a biofilm-associated disease in which Streptococcus mutans plays a central role. This study evaluated HT-2-1-3, a Vespidae venom-derived antimicrobial peptide, as a potential topical anti-caries lead. Methods: Candidate peptides were synthesized by Fmoc solid-phase peptide synthesis and cha...

Synergistic effects of luteolin and Lactobacillus rhamnosus on methicillin-resistant Staphylococcus aureus biofilm inhibition: in vitro and in silico molecular deployment studies.

In Vitro antibacterial, anti-biofilm, and virulence-modulating activity of Cinnamomum verum-mediated iron oxide nanoparticles against carbapenem-resistant uropathogenic Escherichia coli.

These proof-of-concept findings indicate that C. verum-mediated Fe₂O₃-NPs show potent in vitro multi-mechanism antibacterial activity against two clinically confirmed CRE UPEC isolates, combining promising antibacterial potency with transcriptional suppression of key virulence determinants.

3-Hydroxyflavone Inhibits Biofilm Formation and Enhances Antibiotic Activity Against Enterococcus faecalis and Enterococcus faecium

Background/Objectives: The increasing antibiotic resistance of pathogenic bacteria has created an urgent need for new therapies that target virulence factors. Biofilm formation is a major determinant of bacterial pathogenicity and antimicrobial resistance. Methods: Biofilm formation assays (using crystal violet stainin...