Centrosome maintains the integrity of and repairs mature olfactory cilia in adult Drosophila

The microtubule-associated proteins CKAP2 and its paralog CKAP2- Like control ciliogenesis in human cells

It is found that CKAP2-positive cilia are linked to cell cycle progression and that the conserved intrinsically disordered microtubule- binding domain of CKAP2, which is essential for microtubule polymerization and stabilization, is required for its ciliary localization.

Dynamic centrosomes: functional diversity and remodeling across cell types.

Tekt2 regulates hair cell development and function by maintaining normal kinocilium morphology in zebrafish

Background Sensory hair cells (HCs) rely on a highly polarized apical apparatus, composed of actin-rich stereocilia and a microtubule-based kinocilium, to detect mechanical stimuli. Although tektins are conserved microtubule-associated proteins enriched in cilia and flagella, their roles in sensory HC morphogenesis and...

The dynamics of ciliogenesis in prepubertal mouse meiosis reveals new clues about testis maturation

The dynamics of ciliogenesis during mouse puberty are investigated and it is shown that primary cilia are not an intrinsic feature of spermatocytes during the first wave of meiosis, initiated at 8 days post partum (dpp).

Stereotypical interciliary contacts in a C. elegans sense organ

Investigating how primary cilia, structures that detect and transmit signals, form contacts with one another in a head sensory organ of the nematode Caenorhabditis elegans found that these contacts follow consistent patterns and can form even when neighboring cilia are absent, suggesting they are actively established r...

CFAP100 forms phase-separated condensates required for ciliary transition zone assembly

An important role is identified for cilia and flagella associated protein 100 (CFAP100) in the transition zone assembly of the ciliary transition zone, providing insights into the physicochemical principle governing ciliogenesis.