Together, these findings reveal a regional dissociation in spinal gray-matter wiring and suggest a coupling between projection geometry and the distinct processing demands of each segment and statistically characterize neurite orientation across spinal regions.
Understanding the topographic and functional organization of the striatum—a key brain structure involved in motor control, learning, and cognition—is crucial for elucidating the pathophysiology of the neurological and psychiatric disorders associated to it, and for developing targeted therapies. While recent magnetic...
N. Goda, S. Chiken, Daisuke Koketsu et al.· Imaging Neuroscience· 0 citations
Individual differences in cortical folding are a hallmark of human brain anatomy, but what this variability reflects in the underlying tissue remains unclear. Three-hinge gyri (3HGs), where three gyral crests converge, provide an individualized higher-order folding landmark for probing this relationship. Using 7T diffu...
This work developed a surface-based framework to dissociate radial and tangential fiber components within the human SWM and investigated their microstructural properties and functional relevance using in-vivo high-field MRI, providing a foundation for systematic investigation of this complex compartment.
Youngeun Hwang, L. Vavassori, P. Bautin et al.· bioRxiv· 0 citations
The superficial white matter (SWM), a critical brain region for cognition across the lifespan and brain disease, contains abundant short-range association fibers whose organization remains incompletely characterized, in part because the short trajectories and highly variable cortical folding make correspondence across...
Yu-Qian Chen, R. Rushmore, Gui-Kun Chen et al.· 0 citations
Understanding how nervous systems are wired requires methods that provide direct evidence of anatomical connectivity. For more than half a century, tract-tracing approaches based on axonal transport have served as the primary experimental standard for mapping neuronal pathways across central, peripheral, autonomic, and...
Oliver Schmitt, P. Eipert, Rafael Tappe Maestro et al.· Neuroscience and Biobehavior...· 0 citations
Long-range white matter (WM) tracts support cognition by enabling communication between distant cortical regions, which are organized along a hierarchy defined by the sensorimotor-to-association (S-A) axis. However, it remains unknown how WM tracts are positioned within the cortical hierarchy to support cognition. Here...
Joëlle Bagautdinova, G. Shafiei, Audrey C. Luo et al.· Nature Human Behaviour· 1 citation
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