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CytoCrowd: A Multi-Annotator Benchmark Dataset for Cytology Image Analysis

Yonghao Si Xingyuan Zeng Zhao Chen Libin Zheng Caleb Chen Cao Lei Chen Jian Yin
Sep 2026
Machine Learning Computer Vision Human-computer Interaction

Abstract

High-quality annotated datasets are crucial for advancing machine learning in medical image analysis. However, a critical gap exists: most datasets either offer a single, clean ground truth, which hides real-world expert disagreement, or they provide multiple annotations without a separate gold standard for objective evaluation. To bridge this gap, we introduce CytoCrowd, a new public benchmark for cytology analysis. The dataset features 446 high-resolution images, each with two key components: (1) raw, conflicting annotations from four independent pathologists, and (2) a separate, high-quality gold-standard ground truth established by a senior expert. This dual structure makes CytoCrowd a versatile resource. It serves as a benchmark for standard computer vision tasks, such as object detection and classification, using the ground truth. Simultaneously, it provides a realistic testbed for evaluating annotation aggregation algorithms that must resolve expert disagreements. We provide comprehensive baseline results for both tasks. Our experiments demonstrate the challenges presented by CytoCrowd and establish its value as a resource for developing the next generation of models for medical image analysis. The dataset is publicly available at https://github.com/YHSI5358/CytoCrowd-Datasets.

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