Neighborhoods are multifaceted entities whose attributes span sociocultural, economic, and environmental dimensions. Clustering neighborhoods based on social determinants of health (SDoH) can inform the allocation of public health resources and interventions tailored to community needs. Continuous and bounded data, as seen in aggregated neighborhood-level SDoH data, can pose challenges for widely used clustering methods (e.g., k-means or Gaussian mixture models) that rely on Euclidean distances or normality assumptions. Moreover, not all SDoH variables contribute equally to meaningfully characterize neighborhood clusters, and the inclusion of irrelevant or weakly informative determinants can obscure the underlying structure. To address this issue, we propose a Bayesian Salient Multivariate Beta mixture (SAMBA-Mix) model that flexibly models proportional data with embedded feature saliency to identify relevant variables for clustering. Our model showed improved accuracy in cluster identification and structure, compared to existing models. Using data from the U.S. Agency for Healthcare Research and Quality(AHRQ) SDoH database, we demonstrate the utility of our model to derive neighborhood-level SDoH profiles in Massachusetts and identify key determinants that best characterize differences amongst the different profiles.
We propose a novel multivariate hidden Markov model (HMM) designed to analyze longitudinal mixed-type data comprising continuous and ordinal variables. Our model identifies and prioritizes discriminative dimensions, i.e., those useful for clustering, while separating them from noise dimensions. By modeling variables...
M. Ranalli, R. Rocci, A. Maruotti· Journal of Classification· 0 citations
Missing values, atypical observations, and heterogeneity across latent groups are common sources of complexity in regression data. The contaminated Gaussian cluster-weighted model (CG-CWM) provides a natural framework for handling atypical observations, including outliers and leverage points, in model-based clustering....
In high-dimensional omics data, sparse precision matrices of Gaussian graphical models (GGMs) can be used to encode conditional dependence among molecular features to allow for interpretable network inference. This narrative review integrates some of the heterogeneity-aware extensions of GGMs and categorizes them based...
Can-Zhong Zheng· Health and Molecular Frontie...· 0 citations
Multivariate correlated outcomes occur across disciplines, including ecology, social sciences, and psychometrics. This paper focuses on clustering these outcomes across observational units, specifically, finding groups of units with the same ``outcome profile". Our motivation comes from bioregionalization in ecology, w...
Shonosuke Sugasawa, Francis K. C. Hui· 0 citations
Simulations with distribution- and matrix-valued responses show that the proposed spatial distance-clustering framework improves region recovery relative to existing distance-clustering methods, while the frailty layer provides interpretable centrality summaries.
S. Bhattacharyya, Hui-Yan Sang, Bani K. Mallick· 0 citations
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