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Generative Brain Priors-Driven Self-Regulated and Clinically-Guided Multimodal Fusion for Early Alzheimer's Disease Diagnosis.

Aug 2026 · Journal of imaging informatics in medicine · 0 citations · 34 references
Medicine

TL;DR

The proposed GBP-SCMF provides an effective and interpretable multimodal strategy for computer-aided AD diagnosis and integrates three complementary mechanisms: generative brain-prior enhancement to inject disease-related pathological knowledge into imaging representations, self-regulated multimodal alignment to reduce modality bias and feature redundancy, and clinical-imaging collaborative fusion.

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