Jul 2026· 2026 IEEE 27th China Conference on System Simulation Technology and its Applications (CCSSTA)· pp. 332-337· 0 citations· 14 references
Abstract
Cardiovascular disease, as a highly prevalent chronic condition, has shown a continuously rising incidence in China and now ranks as the leading cause of death among both urban and rural residents. Mainstream Cardiovascular disease risk prediction models have mostly been developed based on European and American populations, which do not align well with the physical characteristics and disease patterns of the Chinese population. Moreover, traditional statistical methods have inherent limitations, further restricting the clinical applicability of these models. To address this, the present study constructed a Cardiovascular disease risk prediction model tailored to the Chinese population using machine learning algorithms based on the China Health and Retirement Longitudinal Study database. The dataset was split into a training set and a test set at a ratio of 7:3. Seven algorithms were employed for parallel modeling, and multi-dimensional performance comparisons were conducted. The study found that, in addition to traditional risk factors such as blood pressure and blood glucose, sleep indicators—including nap duration and nighttime sleep duration—were also important influencing factors for Cardiovascular disease. The comparative results demonstrated that the LightGBM model achieved the best predictive performance, with an AUC of 0.828, a recall of 0.717, and an F1 score of 0.568. The integration of SHapley Additive exPlanations further validated the internal logic and rationality of the model. This model can assist clinicians in risk assessment, thereby effectively improving the accuracy and efficiency of cardiovascular disease prediction.
Cardiovascular Diseases (CVDs) continue to be one of the leading causes of deaths in the world, claiming some 17.9 million lives every year. This burden is higher in Pakistan because of "Asian Indian Phenotype" which makes them vulnerable to early coronary artery disease. The commonly used traditional risk prediction models, including the Framingham Risk Score, have been developed in Western populations and are poorly predictive in South Asian populations. This study aims to fill this important gap by designing, implementing and comparative evaluation of six supervised machine learning algorithms for early detection of cardiovascular disease using a locally collected clinical dataset of 411 patient records with 13 independent clinical attributes. The models tested are Logistic Regression, K Nearest Neighbor, Support Vector Machine, Random Forest, Gradient Boosting and XGBoost. A rigorous gender-based mean imputation and Z-score normalization was done and split in 80/20 ratio. Empirical results show that the Random Forest classifier has Area under the Curve (AUC) of 0.9842, accuracy of 95.2%, precision of 96.0% and recall of 96.0%. The model was then exported and used to create a browser-based, predictive application that could be embedded in an interactive dashboard for real-time cardiovascular risk without the need for a server. These results confirm the effectiveness of ensemble learning approaches for medical diagnostics and highlight the potential of implementing ML-based screening tools in the limited resource healthcare environment in Pakistan.
Awais Khursheed, Soban Ahmed, Sibghat Ullah et al.· International Journal of Inn...· 0 citations
Six supervised learning models were developed and compared for diabetes prediction using a dataset and compared for diabetes prediction using a 100k patients records with eight clinical features including gender, age, hypertension, smoking history, heart disease, BMI, HbA1c level, and blood glucose level.
There is an urgent need for explainable, clinically validated and standardised ML frameworks to translate predictive models into routine healthcare practice and improve early detection of cardiovascular disease.
Hanna Rasheed, Arya.K.R Arya.K.R, Ashida.K.A Ashida.K.A· International Journal of Tec...· 0 citations
Male sex was a statistically significant independent predictor of heart disease after controlling for other clinical variables and the findings support sex-specific screening and preventive strategies for high-cholesterol male patients and demonstrate the value of interpretable machine learning models for clinical decision support.
Taiwo Samson Adeyemo· GSC Advanced Research and Re...· 0 citations
Diabetes is a major risk factor for the development of cardiovascular issues which contribute to cardiovascular disease (CVD) being a leading cause of mortality worldwide. However, traditional machine learning methods are not widely adopted in healthcare systems because they lack interpretability, which is important for early and accurate CVD risk prediction and for ruling out effective clinical intervention. In this research, a hybrid architecture is proposed that incorporates diabetes related datasets as well as explainable artificial intelligence (XAI) methodologies that could improve the prediction power and transparency of the models. The proposed approach combines different datasets at the level of features and includes rigorous data pre-processing to detect metabolic and cardiovascular risk factors. Some of the significant clinical parameters are age, BMI, glucose, cholesterol, and blood pressure. These are standardized to create a single dataset which may be utilized for predictive modelling. The employment of two XAI approaches, SHAP (SHapley Additive Explanations) with tree-based ensemble models and integrated gradients with transformer based topologies, ensures both performance and interpretability. The technique improves confidence and usefulness in clinical settings by offering accurate predictions and explanations for the model’s judgments that are relevant to the circumstance. It is also utilized for visual investigation of clinical correlations of diabetes and cardiovascular disease and identify crucial risk variables. The results suggest that merging explainability approaches with powerful machine learning can considerably boost early identification and risk assessment. The proposed approach contributes to enhanced healthcare decision-making, offering a scalable, interpretable and dependable solution for cardiovascular disease prediction.
K. Deepthi, P. Bhargavi· International journal of com...· 0 citations
The results demonstrate that ML models can effectively identify individuals at high risk of hypertension, offering a valuable tool for early intervention and personalized healthcare and underscores the potential of artificial intelligence in supporting public health efforts and enhancing clinical decision-making.
G. Vamsi, K. Bhargavi· International Scientific Jou...· 0 citations
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