Jul 2026· International Journal for Sciences and Technology· 0 citations· 8 references
TL;DR
The findings suggest that Logistic Regression is more suitable as a decision-support model for early heart disease screening due to its higher sensitivity, accuracy, and specificity.
Abstract
Heart disease remains one of the leading causes of mortality worldwide, highlighting the importance of accurate and timely prediction models to support early clinical decision-making. Objective: This study aims to compare the predictive performance of Logistic Regression and K-Nearest Neighbor (KNN) algorithms for heart disease classification and to identify the most appropriate model for early screening. Methodology: A quantitative comparative research design was employed using the Cleveland Heart Disease dataset from the UCI Machine Learning Repository, consisting of 303 patient records. The data were divided into training and testing sets using an 80:20 split. Logistic Regression was developed using backward stepwise selection, while KNN used standardized numerical variables with K = 15. Model performance was evaluated using accuracy, sensitivity, specificity, and precision. Findings: Logistic Regression outperformed KNN by achieving an accuracy of 83.6%, sensitivity of 93.5%, specificity of 73.3%, and precision of 78.4%. In comparison, KNN achieved an accuracy of 80.3%, sensitivity of 89.5%, specificity of 65.2%, and precision of 81.0%. These results indicate that Logistic Regression provides more reliable overall performance, particularly in identifying patients with heart disease. Implications: The findings suggest that Logistic Regression is more suitable as a decision-support model for early heart disease screening due to its higher sensitivity, accuracy, and specificity. This model may support healthcare professionals in identifying at-risk patients and reducing the likelihood of missed heart disease cases. Originality: The originality of this study lies in its transparent comparison of Logistic Regression and KNN using a standardized benchmark dataset while emphasizing clinically relevant evaluation metrics, particularly sensitivity. This approach provides additional empirical evidence for selecting interpretable machine learning models in clinical prediction tasks.
Male sex was a statistically significant independent predictor of heart disease after controlling for other clinical variables and the findings support sex-specific screening and preventive strategies for high-cholesterol male patients and demonstrate the value of interpretable machine learning models for clinical decision support.
Taiwo Samson Adeyemo· GSC Advanced Research and Re...· 0 citations
The research work concludes that ML models, when properly tuned and validated, can significantly assist in the early diagnosis of heart disease, offering critical support for clinical decision-making.
Cardiovascular Diseases (CVDs) continue to be one of the leading causes of deaths in the world, claiming some 17.9 million lives every year. This burden is higher in Pakistan because of "Asian Indian Phenotype" which makes them vulnerable to early coronary artery disease. The commonly used traditional risk prediction models, including the Framingham Risk Score, have been developed in Western populations and are poorly predictive in South Asian populations. This study aims to fill this important gap by designing, implementing and comparative evaluation of six supervised machine learning algorithms for early detection of cardiovascular disease using a locally collected clinical dataset of 411 patient records with 13 independent clinical attributes. The models tested are Logistic Regression, K Nearest Neighbor, Support Vector Machine, Random Forest, Gradient Boosting and XGBoost. A rigorous gender-based mean imputation and Z-score normalization was done and split in 80/20 ratio. Empirical results show that the Random Forest classifier has Area under the Curve (AUC) of 0.9842, accuracy of 95.2%, precision of 96.0% and recall of 96.0%. The model was then exported and used to create a browser-based, predictive application that could be embedded in an interactive dashboard for real-time cardiovascular risk without the need for a server. These results confirm the effectiveness of ensemble learning approaches for medical diagnostics and highlight the potential of implementing ML-based screening tools in the limited resource healthcare environment in Pakistan.
Awais Khursheed, Soban Ahmed, Sibghat Ullah et al.· International Journal of Inn...· 0 citations
Stroke is one of the leading causes of death and disability worldwide, requiring an accurate machine learning-based risk prediction approach to support early detection. This study aims to conduct a comparative evaluation of three supervised learning algorithms, namely Naïve Bayes, Random Forest, and SVM, in predicting stroke risk. The clinical dataset used consisted of 5,110 patients. Model evaluation was performed using the Stratified 5-Fold Cross Validation method, a cross-validation technique that divides the data into five subsets while maintaining the class proportions in each fold. Each subset is alternately used as test data, while the other subset is used as training data, so that all data can be used as training data and test data. Model performance was measured using accuracy, confusion matrix, and AUC-ROC metrics to assess classification performance. The results showed that Random Forest achieved the best performance with an accuracy of 95%, followed by Naïve Bayes at 86% and SVM at 75%. Based on the AUC-ROC evaluation, Random Forest also showed the most optimal performance with a value of 0.80, indicating excellent classification ability. Random Forest is the most effective algorithm in predicting stroke risk in the dataset used, so it has the potential to be the best method used to support the early stroke detection system.
Alya Masitha, H. M. Jumasa, Wellie Sulistijanti et al.· Rabit : Jurnal Teknologi dan...· 0 citations
This study investigated the application of machine learning techniques and exploratory data analysis to forecast early-onset of diabetes using the PIMA Indian dataset, finding promising results.
Abdulrahman Nasiru Sada, Eli. A. Jiya, Yahaya Muhammad Umar et al.· Journal of Science Research...· 0 citations
It is demonstrated that machine learning models can effectively identify high-risk patients and that minority data resampling significantly improves mortality classification reliability, and the approach offers potential value for clinical decision support systems and prioritised care pathways.
Abiodun Ojo· Journal International Review...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
