Sep 2026· Journal of Diabetes and Metabolic Disorders· Vol 25· 0 citations· 21 references
Medicine
TL;DR
The MTHFR C677T polymorphism is relatively common among elderly women in southern Iran and the lower T allele frequency compared with global populations highlights potential regional genetic variation within the Iranian population.
It is suggested that certain polymorphisms in the MTHFR gene may contribute to the risk of recurrent miscarriage, although their impact appears to be limited in the studied population.
Rahaf Mohammed Tuurki, M. S. Farman· International Journal of Bio...· 0 citations
Background: Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in folate metabolism. Polymorphisms of the MTHFR gene, particularly C677T and A1298C, can reduce enzyme activity and lead to elevated homocysteine levels. This, in turn, may contribute to placental vascular disease and endothelial dysfunction, whic...
N. Suliman, K. Bakheit, K. Awadalla et al.· Sudan Journal of Medical Sci...· 0 citations
Objective: To investigate the association between the TCF7L2 rs7903146 polymorphism and type 2 diabetes mellitus susceptibility in a southern Iraqi population
Study Design: Case-control studyPlace and Duration of Study: This study was conducted at the Al-Fayhaa Teaching Hospital, Basrah, Iraq, from 1st November 2025 to...
Manar Qasim Mohammed, A. Saleh· Medical Forum Monthly· 0 citations
Objective: The CDKAL1 rs7754840 G>C polymorphism is link to defective insulin release and an elevated risk of type 2 diabetes mellitus. The objective of the current research was to identify the frequencies of alleles and genotypes for the rs7754840 G>C polymorphism in healthy Turkish individuals and to contrast them wi...
Zuhal Uçkun Şahinoğulları· Ankara Universitesi Eczacili...· 0 citations
The CYP1A1 rs1048943 polymorphism was not associated with laryngeal cancer susceptibility in this Sudanese cohort, and larger studies are needed to clarify the genetic basis of laryngeal carcinogenesis.
Marwa Abdalwahab, M. Ellaithi· F1000Research· 0 citations
The incidence of breast cancer development was found to be elevated among females carrying the thymine-cytosine genotype, whereas the thymine-thymine genotype played a protective role among the healthy subjects.
Varda Ramzan, F. Farooq, A. Rahim et al.· JOURNAL OF PAKISTAN MEDICAL...· 0 citations
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