The results are consistent with structured, feedback-derived error memory being useful for adapting clinical coding behavior across cases without weight updates or changes to the underlying workflow.
Abstract
Clinical coding agents repeatedly encounter the same failure modes, including unsupported codes, missed documented conditions, specificity errors, and procedure-coding convention mismatches. We introduce Learn-Then-Act, an inference-time adaptation framework that converts errors from a small labeled LEARN batch into a structured Mistake Knowledge Database (MistakeKDB). False-negative lessons are routed to a recall-oriented Coder, while false-positive lessons are routed to a precision-oriented Judge. We instantiate the framework in LearnActCoder, a Coder-Judge clinical coding pipeline with lookup-table grounding where available. On 150 matched MIMIC-III notes, structured MistakeKDB improves CPT F1 by 5.9 percentage points, while raw-example and reflection-style memories remain near the no-memory baseline; the ICD-9 improvement is not significant. On a matched MIMIC-IV cohort, memory shifts ICD-10 coding toward higher precision at a recall cost, leaving F1 statistically unchanged. Applying the same memory to 1,000 held-out MIMIC-III notes maintains a stable ICD operating point, providing scale/stability evidence. Overall, the results are consistent with structured, feedback-derived error memory being useful for adapting clinical coding behavior across cases without weight updates or changes to the underlying workflow. Absolute CPT/HCPCS performance remains low, and the system is evaluated retrospectively rather than in clinical deployment.
CAST (Concept-guided Artifact Suppression Tuning), an SAE-based framework for auditable clinical text classification, improves over its corresponding fine-tuned encoder baselines and remains competitive with strong LLM baselines, while producing a feature-level audit trail of the clinical concepts that support each pre...
In automated clinical coding, where the label space spans tens of thousands of diagnosis and procedure codes, models are currently evaluated against a single gold annotation, treating any deviation as error. But we find when two teams code the same 110 ACI-Bench encounters, they agree on only 73% of codes (Jaccard simi...
Han-Chin Shing, Jack Moriarty, Ryan Ware et al.· 0 citations
Next-encounter ICD forecasting predicts which standardized diagnosis codes will be documented at a future visit from the longitudinal record available beforehand. The task is prospective and multi-label: the target note does not yet exist, and several codes may be correct. Structured EHR foundation models capture recur...
Junda Wang, Meysam Ghaffari, Akshat Choube et al.· 0 citations
This work proposes Knowledge-Guided Reasoning over Clinical Evidence with LLMs (KREL), a framework that leverages LLMs for clinical text understanding and reasoning while integrating external ICD coding guidelines as structured knowledge, and enables tight coupling between domain knowledge and LLM reasoning.
Xubin Chen, Yi-Peng Zhou, Wenxin Sun et al.· 0 citations
Objective Translating free-text clinical trial criteria into computable code sets is a valuable standardization practice that is necessary for producing reproducible real-world evidence studies but requires standardized interpretation across multiple clinical vocabularies. Methods We developed TrialCode Agent, a hybrid...
A. Habibdoust, A. Sajjad, D. Hernández et al.· medRxiv· 0 citations
Large language models (LLMs) are increasingly used to compute clinical risk scores from free-text notes. Notes are often incomplete, and treating undocumented findings as normal can silently misclassify patients. We test whether separating three-state extraction (present, absent or unknown, by an LLM) from decision log...
With $2.1 million funding from Google.org, the open-source Public Transit Intelligence Hub will unify public transit monitoring, operations, and passenger communication.
Professor Sherry Turkle’s new book, “Artificial Intimacy,” offers a withering critique of chatbots and the antisocial dynamics she believes they encourage.
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