Jul 2026· World Journal of Pediatrics· Vol 22, pp. 741 - 754· 0 citations· 30 references
Medicine
TL;DR
Adjusting the risk stratification based on treatment response significantly improved the overall prognosis of T-LBL, and molecular genetic risk factors might contribute to further risk stratification and provide potential therapeutic targets.
Survival outcomes in this cohort are markedly lower than in high-income countries, and improving survival requires complementing biological risk stratification with targeted strategies to overcome socioeconomic barriers and prevent treatment non-adherence.
Francisca Morales-Vital, Diego Moreno-Loaeza, V. M. Alvarado-Castro et al.· Journal of Clinical Medicine· 0 citations
Introduction Data on clinical outcomes and allogeneic stem cell transplantation for Latin American Philadelphia chromosome-negative acute lymphoblastic leukemia patients are limited. This study aimed to characterize this population and identify factors influencing overall survival among adolescents and adults with this...
M. M. Clavijo, J. Ruiz, Luciana Ferrari et al.· Hematology, Transfusion and...· 0 citations
BACKGROUND
TP53 mutations confer poor prognosis and heterogeneous clinical features in myeloid neoplasms, but distinguishing factors between AML and MDS and independent prognostic markers within this high-risk group remain unclear.
METHODS
This retrospective study evaluated 45 adult patients with TP53-mutated acute m...
Introduction: Metastatic bladder cancer (mBC) is associated with poor outcomes. Despite advances in immunotherapy and targeted agents, platinum-based chemotherapy remains a cornerstone of treatment in real-world practice. We aimed to identify pragmatic and readily available prognostic factors for risk stratification in...
Zeynep Alaca Topçu, M. Ozturk, M. Yıldırım et al.· Haydarpasa Numune Training a...· 0 citations
Background Tumor regression grade (TRG) after neoadjuvant therapy has been proposed as a prognostic marker in resectable gastroesophageal adenocarcinoma, yet its independent value beyond pathological staging remains uncertain. Materials and methods This retrospective single-center study included 692 patients with local...
H. Puhr, B. Mozayani, M. Korpan et al.· ESMO gastrointestinal oncolo...· 0 citations
BACKGROUND
Composite scores such as Lung Immune Prognostic Index (LIPI), modified Glasgow Prognostic Score (mGPS), EPSILoN, Pan Immune-Inflammation Value (PIV) and Systemic Immune-Inflammation Index (SII) have shown prognostic value in solid tumors, but evidence in extensive-stage small-cell lung cancer (ES-SCLC) are l...
Teresa Beninato, Giulia Stasi, G. Montelatici et al.· Tumori· 0 citations
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