Aug 2026· Therapeutic Advances in Infectious Disease· Vol 13· 0 citations· 15 references
Medicine
TL;DR
An extremely rare case of melioidosis complicated by pericardial effusion and cardiac tamponade is reported, which was successfully treated with pericardiocentesis and appropriate antimicrobial therapy.
Abstract
Melioidosis is a serious infectious disease caused by Burkholderia pseudomallei, a bacterium endemic to tropical regions, including Taiwan. The disease can involve multiple organs; however, cardiac involvement, particularly cardiac tamponade, is rare. To date, only four cases of melioidosis presenting with cardiac tamponade have been reported in the literature. Here, we report an extremely rare case of melioidosis complicated by pericardial effusion and cardiac tamponade, which was successfully treated with pericardiocentesis and appropriate antimicrobial therapy.
Melioidosis, caused by the gram-negative bacillus Burkholderia pseudomallei - a Tier 1 Select Biological agent - remains a significant cause of severe community-acquired infection in tropical regions, but with recent expanding recognition in temperate climates, including the United States. Pulmonary involvement is the...
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