TL;DR
A-Zr phyto-nanohybrids synthesized via a green method exhibit significant hepatoprotective potential against CCl₄-induced liver injury, supporting their role as a sustainable nanomedicinal strategy for chemically induced hepatotoxicity.
Hepatorenal toxicity stems from chronic oxidative stress (OS) generated from mechanisms underlying chemical or metabolic injury. The present study investigates the hepatorenal toxicity induced by carbon tetrachloride (CCl4) and alloxan, and the hepatorenal-protective potential of Berberine-loaded (BBR) silver–zinc oxid...
Paracetamol is the most common cause of drug- induced liver injury, which is associated with oxidative stress, cytokine release, and apoptosis. Boswellic acid (BA), with anti- inflammatory and antioxidant effects, can ameliorate liver injury but has poor solubility and bioavailability. The objective of this study w...
This study provides the first demonstration that asiatic acid exerts robust systemic antioxidative, hepatoprotective, and neuroprotective effects against CPF-induced toxicity, highlighting AA’s therapeutic potential for mitigating organophosphate pesticide poisoning.
It is demonstrated that radiation-synthesized gallotannin hydrogel (GTH) exerts nephroprotective effects against ATO-induced nephrotoxicity, driven by antioxidant, anti-inflammatory, and anti-apoptotic mechanisms mediated via modulation of the miR-223/TXNIP axis.
It is suggested that the developed Polyherbal combination (2:1:1) and its prepared nanoparticles exhibit chemopreventive effects against HCC and could be used as adjuvant therapy.
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