Association of TCF7L2 and LEPR gene variants (rs7903146 and rs1137101) with primary knee osteoarthritis in a northern Mexican Mestizo population.

CDKAL1 rs7756992 polymorphism and the risk of type 2 diabetes among Moroccans: A systematic review and meta-analysis.

The CDKAL1 rs7756992 polymorphism is an established type 2 diabetes mellitus (T2DM) susceptibility locus; however, its role in the Moroccan population remains poorly characterized. This study provides the first rigorous meta-analysis of this variant in Morocco, following the PRISMA guidelines (PROSPERO: CRD42024549118)...

Association of IL16 rs11556218 and IL1B rs16944 polymorphisms with type 2 diabetes in the Kinh Vietnamese population

Background Type 2 diabetes mellitus (T2DM) is a multifactorial metabolic disease in which inflammatory mechanisms are involved in disease development and progression. Polymorphisms in cytokine-related genes may influence susceptibility to T2DM, yet evidence in Vietnamese individuals remains scarce. This study was desig...

Association Of VDR (Apai Rs7975232) Polymorphism And Some Biochemical Parameters With Psoriasis In Iraqi Patients

The A allele of the VDR ApaI (rs7975232) gene polymorphism was associated with increased susceptibility to psoriasis in Iraqi patients and AA carriers showed the lowest mean vitamin D3 and zinc levels and the highest mean ferritin level; however, genotype-related differences in these biochemical parameters were not sta...

Dopamine Receptor D2 gene Polymorphisms rs2005313, rs4274224, and rs4938019 in Pakistani Patients with Schizophrenia:a Diagnostic Tool for Schizophrenia

The research identified highly significant associations across multiple inheritance models, validating the technical robustness of the findings, and establish DRD2 intronic polymorphisms as critical determinants of schizophrenia risk.

IGF-1 gene polymorphisms (rs35767, rs6218, rs6212, rs972936, and rs6214) and the progression of diabetic retinopathy (DR) in Iraqi patients

The analysis of IGF-1 gene polymorphisms revealed significant genotype differences among the DR, DNR, and control groups, and it is worth noting that patients suffering from secondary complications of diabetes such as neuropathy and nephropathy were excluded, as were female participants.

Association of a near-MC4R gene variant (rs17782313) with hyperphagia among patients with severe obesity