NF-κB/NLRP3 inflammasome is associated with formaldehyde-induced reproductive and metabolic dysfunction: protective role of quercetin in rats

Arnab Banerjee Jayati Roy Arnab Banerjee Aditi Banerjee Puja Datta Debasmita Das Rajarshi Paul Diptendu Sarkar Arindom Halder Krishnendu Manna S. Mukherjee B. Maji

Aug 2026 · Molecular Biology Reports · Vol 53 · 0 citations · 54 references

Medicine

TL;DR

Initial evidence that formaldehyde triggers DAMP-associated sterile inflammation with disruption of metabolism and reproduction is provided and the potential benefit of quercetin treatment as a nutraceutical against environmental aldehydes by suppressing multitarget pathways is demonstrated.

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