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Zu-Jian Zhang

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Open access Sep 2026

Integrative single-cell and bulk transcriptomic analysis identify R-loop-associated gene signatures driving immune-inflammatory networks in acute pancreatitis

R-loop dysregulation has been implicated in chronic inflammation via DNA damage and cytoplasmic ssDNA release, yet its role in acute pancreatitis (AP) remains to be systematically investigated. This study aimed to identify R-loop-related biomarkers in AP and elucidate their potential roles in immune-inflammatory...

Lu-Juan Pan, Wei-Bang Wu, Tian-Ying Zhang et al. · 0 citations

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