Author

Zsu-Zsu Chen

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Open access Aug 2026

Genetic drivers of protein changes over time: Findings, considerations, and approaches in TOPMed cohorts and UK Biobank

Age is a major risk factor for many diseases, but the biological processes driving aging are heterogeneous across individuals. Efforts to untangle differences between chronological and biological age have focused on identifying age-associated markers, such as ’omics clocks. Many ’omics features, including proteins, are...

M. Gillman, H. Chen, A. Howard et al. · bioRxiv · 0 citations

Jul 2026

Proteomic signatures of loss of glycemic control in youth-onset type 2 diabetes in the TODAY study.

Novel proteins involved in axon guidance, immune response, inflammation, and metabolism associated with LOGC in youth-onset T2D with proteins demonstrating consistent associations across the lifespan and proteomic platforms are identified.

K. Tommerdahl, Kristen R. Miller, Jian-Jun Liu et al. · Journal of Clinical Endocrin... · 0 citations