African swine fever virus pA137R inhibits type i interferon signal transduction by interacting with TYK2 and impairing STAT1/2 activation.
African swine fever virus (ASFV) pA137R is a key immune evasion protein known to target TBK1 and suppress the cGAS-STING pathway; however, whether it modulates type I interferon (IFN) signal transduction remains unknown. In this study, we investigated the role of the A137R protein (pA137R) in the JAK-STAT type I IFN si...