KAT6A inhibitor-loaded and anti-PD-L1-coated manganese metal–organic framework nanoplatform for enhanced colorectal cancer immunotherapy via cGAS-STING activation
Colorectal cancer immunotherapy remains limited by insufficient innate immune activation, poor tumor immune infiltration, and resistance to immune checkpoint blockade. Herein, we developed a KAT6A inhibitor-loaded and anti-PD-L1-coated manganese metal-organic framework (MnMOF) nanoplatform for enhanced colorectal cance...