Zoe A. Fisk

SARS-CoV-2 spike-armed vesicular stomatitis virus recapitulates severe COVID-19 acute respiratory distress syndrome in mice

Summary Clinically relevant preclinical models are critical for understanding acute respiratory distress syndrome (ARDS) and developing novel therapeutics. Although SARS-CoV-2 pseudovirus-based models overcome biosafety challenges associated with live coronavirus, their ability to recapitulate key ARDS features and res...