Ziyue Wang

The SaeRS two-component system likely mediates the major dopamine-dependent regulation of virulence in Staphylococcus aureus ATCC 25,923

Dopamine was taken up by the bacteria and was associated with enhanced pathogenic phenotypes, including increased proliferation, toxin production, biofilm formation, motility, adhesion, and multidrug resistance and deletion of saeS markedly attenuated these dopamine-associated effects.