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Author

Ziyin Wang

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Open access Jul 2026

Toward a Pan-Arenavirus T-cell Vaccine: Identification and Preclinical Evaluation of Conserved Epitope constructs 2260477

This work identified Conserved T cell Epitope Regions (CTERs) derived from conserved sequences within OWA and NWA, using LASV and JUNV as respective prototypes and represents an initial step toward the development of a pan-arenavirus T-cell vaccine.

Ziyin Wang, Margret Kim, A. Zúñiga et al. · 0 citations
Jul 2026

Bivalent vaccination fails to enhance conserved spike T cell responses across BetaCoronaviruses 2260452

It is suggested that spike-based bivalent vaccination alone cannot direct a T-cell focused response to achieve broad immunity across the BetaCoronavirus family, and incorporation of additional protein sequences will likely be required to shift response toward the CTER approach.

Ziyin Wang, Nematullah Waseem, Naomi Peisajovich et al. · 0 citations

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