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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Zirong Jiang

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Open access Aug 2026

TRIB3 promotes triple-negative breast cancer metastasis by restricting lipophagy through the PI3K/AKT/mTOR signaling pathway.

BACKGROUND Lipophagy-driven metabolic reprogramming is increasingly recognized as a determinant of tumor progression. TRIB3, a key regulator of lipid metabolism, has been implicated in cancer aggressiveness, with elevated expression linked to poor outcomes in triple-negative breast cancer. Here, we investigated whether...

L. Ruan, Jian-Feng Liu, Zirong Jiang · 0 citations

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