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Zihan Ma

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Open access Aug 2026

An orthogonal transcription system enables high-efficiency rescue of measles virus-based vaccine vectors against multiple pathogens

A modular, helper-virus-free and high-efficiency rescue platform based on an orthogonal transcription system utilizing orthogonal promoters and engineered RNA polymerases fused to an mRNA capping enzyme is developed and provides a proof-of-concept methodological framework for the rapid development of vaccine candidates.

Zihan Ma, Weijun Wang, Qiuli Lou et al. · 0 citations

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