Open access
Sep 2026
Acteoside alleviates slow transit constipation with attenuation of NLRP3 inflammasome activation and preservation of enteric neurons
Background Slow transit constipation (STC) is characterized by delayed intestinal transit and impaired defecation, with enteric nervous system (ENS) injury and inflammatory dysregulation contributing to its pathogenesis. Acteoside (ACT), a natural phenylethanoid glycoside, has anti-inflammatory and neuroprotective prop...
Bao-Hong Zhao, Ya-Qian Ping, Xiao-Hui Dou et al.
· Frontiers in Pharmacology · 0 citations