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Author

Zi-Yi Chen

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Oct 2026

Neuroactive gypenosides from Yunnan Gynostemma pentaphyllum: Nrf2-mediated cytoprotection and cholinesterase inhibition.

Findings demonstrate clear regional differences in pharmacological efficacy among the five samples, identify new gypenosides from ZTB with both cholinesterase-inhibitory and cytoprotective activities in vitro, and provide preliminary scientific validation for the ethnopharmacological application of ZTB in the context o...

Hong-Xia Zhang, Hui-Wei Zhou, Zi-Yi Chen et al. · 0 citations
Review Open access Aug 2026

Research progress and application prospects of multi-omics integration strategies in precision risk stratification of type 1 diabetes mellitus

This narrative review critically evaluates how multi-omics integration strategies can improve precision risk stratification throughout the T1D disease continuum by integrating complementary molecular information from genomics, transcriptomics, proteomics, proteomics, metabolomics, epigenomics, and the microbiome.

Zi-Yi Chen, Wen-Tao Liu, Zheng Guo et al. · 0 citations

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