Smilax glabra flavonoids ameliorate non-alcoholic steatohepatitis by regulating PKM2-dependent glycolysis and suppressing AIM2 inflammasome activation
Background Nonalcoholic steatohepatitis (NASH) is a prevalent chronic liver disease characterized by hepatic steatosis, persistent inflammation and progressive liver damage. Smilax glabra flavonoids (SGF), the major bioactive constituents of Smilax glabra Roxb., exhibit potent antioxidant and anti-inflammatory activiti...