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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

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Zi-Han Zhang

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Aug 2026

Probing the Catalytic Promiscuity and Enhancing the Efficiency of CYP725A4 with a Taxadiene Substrate Mimic

The catalytic promiscuity of cytochrome P450 CYP725A4 severely impedes paclitaxel biosynthesis, as it generates taxadien-5α-ol (T-5α-ol) alongside numerous by-products. Despite diverse proposed mechanisms and the reported role of facilitator of taxane oxidation (FoTO1) in promoting T-5α-ol formation, conclusive evide...

Long-Hao Huang, Ming-Yuan Lai, Zi-Han Zhang et al. · 0 citations

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