Zi-Han Feng

Vibrio vulnificus hemolysin drives NLRP3 inflammasome activation in platelets via TRPC6-mediated calcium signaling.

Vibrio vulnificus, an opportunistic pathogenic species, predominantly induces sepsis in patients with liver disease rather than in healthy individuals, although its opportunistic pathogenic mechanisms are unclear. The role and mechanisms behind the NLRP3 inflammasome activation induced by V. vulnificus infection in nor...