Convergent evolution of viral nucleases targeting cyclic dinucleotides
Poxviruses, African swine fever virus (ASFV), and bacteriophages have independently evolved nucleases that degrade cyclic dinucleotides (CDNs), which are critical second messengers that mediate antiviral responses. This Pearl synthesizes recent advancements in our understanding of viral CDN-degrading nucleases and emph...
Zi-Chen Li, Lei-Liang Zhang
· PLoS Pathogens · 0 citations