Ginkgolide B Mitigates Doxorubicin-Induced Cardiotoxicity by Regulating AMPK-Mediated Mitochondrial Fission via P-Drp1/OPA1 and Apoptosis.
BACKGROUND Doxorubicin (DOX) is an effective chemotherapeutic agent but is limited by its severe cardiotoxicity, causing mitochondrial dysfunction and apoptosis in cardiomyocytes. Ginkgolide B, derived from Ginkgo biloba, shows potential cardioprotective effects. OBJECTIVE To investigate the protective effects of Gin...