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Author

Zhuo-Qun Su

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2 papers indexed here

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Oct 2026

Multiplexed Small-Molecule Detection Using Sequence-Defined DNA Reporters in an Argonaute−Nanopore System

Multiplexed small-molecule detection remains challenging because chemically diverse analytes lack universal amplification and encoding mechanisms. Here, we present SMART-pore, a programmable molecular encoding-decoding platform, that converts target recognition events into sequence-defined DNA reporters and resolves...

Zhuo-Qun Su, Jing-Xian Hou, Liu-Xin Jiao et al. · 0 citations
Sep 2026

A Peptidoglycan-Mimetic Nanopore Receptor Resolves Glycopeptide Antibiotic Recognition and Resistance at the Single-Molecule Level.

Glycopeptide antibiotics (GPAs) are a critical class of last-resort therapeutics for treating severe infections caused by multidrug-resistant Gram-positive bacteria. However, their highly similar molecular structures and binding mechanisms make accurate discrimination and mechanistic analysis challenging. Here, we repo...

Zhuo-Qun Su, Liu-Xin Jiao, Jing-Xian Hou et al. · 0 citations

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