CellRFT: Reinforcement Fine-Tuning for Single-Cell Perturbation Modeling
Predicting cellular responses to perturbations supports the study of gene function, disease mechanisms, and therapeutic strategies. Despite advances in single-cell perturbation modeling, existing models typically optimize surrogate losses that do not directly reflect the biological criteria used for evaluation, so bett...
Jie Yan, Li Liu, Han-Ze Guo et al.
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