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Author

Zhong-Wei Niu

2 papers indexed here

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Aug 2026

Mannose-modified tobacco mosaic virus-mediated macrophage regulation inhibits pulmonary fibrosis progression.

Idiopathic pulmonary fibrosis (IPF) is a chronic disease, causing irreversible lung scarring and respiratory failure. CD206+ M2 macrophages play a key role in its progression. In this study, we utilize the pro-inflammatory properties of plant viruses to develop a mannose-modified tobacco mosaic virus nanoparticle (TMV-...

Jiaodan Jin, Ren Xu, H. Fu et al. · 0 citations
Sep 2026

A 4-Arm polyethylene-glycol-based multivalent galactoside disrupts Pseudomonas aeruginosa biofilm and restores antibiotic susceptibility.

Results indicate that 4-Arm-PEG-Gal significantly disrupts mature biofilm and is specifically recognized by the lectin LecA, and compared to the use of antibiotics alone, the combination of 4-Arm-PEG-Gal and TOB reduces antibiotic usage by 75% and additionally eradicates 73% of the bacteria within the biofilm.

Chen-Xiao Wan, Xiaoyan Ju, Mei-Yun Ma et al. · 0 citations

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