Jul 2026
Prdm15 deficiency perturbs hematopoietic stem and progenitor cell homeostasis.
It is reported that Prdm15 deficiency in HSPCs induces the accumulation of immature hematopoietic stem cells in mice, establishing PRDM15 as a critical epigenetic regulator of HSPCs, offering valuable insights into the molecular mechanisms underlying hematopoietic homeostasis.
Qi-Wen Dong, Wei-Wei Xiao, Junsong Huang et al.
· Journal of genetics and geno... · 0 citations