Open access
Sep 2026
Hypoxia confers ferroptosis resistance in glioma cells via HIF-1α/SREBP1-mediated regulation of lipid metabolism
The role of the HIF-1α-SREBP1-FASN/SCD1 signaling axis in ferroptosis regulation in glioma is systematically elucidated, providing important theoretical foundations and experimental support for developing HIF-1α-targeted ferroptosis therapies.
Zhong-Jun Shen, Yao Zhao, Ming-Bo Jia et al.
· Journal of Lipid Research · 0 citations