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Zhong-Hua Xiong

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Open access Sep 2026

Vagus Nerve Stimulation Exerts Disease-Modifying Effects in Epileptic Rats by Enhancing Hippocampal Adenosine Signalling.

OBJECTIVES Vagus nerve stimulation (VNS) is an established neuromodulatory therapy for refractory epilepsy, but its disease-modifying mechanisms remain unclear. Adenosine is an endogenous anticonvulsant and a key regulator of epileptogenesis, and adenosine kinase (ADK) controls extracellular adenosine availability. Thi...

Zhong-Hua Xiong, Jing Zhang, Ran Gao et al. · 0 citations

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