Sep 2026
High-yield production of immunogenic PV3 virus-like particle in yeast.
The identification of thermally stabilized mutants of all three poliovirus serotypes (PV1, PV2, and PV3) has enabled the development of virus-like particle (VLP)-based next-generation poliovirus vaccines. PV3 stabilized mutant-derived VLPs (sVLPs) have been produced in several recombinant systems through co-expression...
Tian Chen, Qin Hong, Wen-Yu Han et al.
· Antiviral Research · 0 citations