Author

Zhiyuan Zhong

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Open access Aug 2026

ROS-responsive nanogels enable inhaled CD24 immunotherapy for selective hyperinflammation suppression in severe pneumonia

Acute pneumonia triggered by pathogen infection and lung injury persists as a critical global life-threatening issue. Cluster of differentiation 24 (CD24), by selectively inhibiting the inflammatory response associated with damage-associated molecular patterns (DAMPs) through the interaction with Siglec, has appeared a...

Xin Wang, Xiaofei Zhao, Fan Zhang et al. · Science Advances · 0 citations

#protein folding Open access Aug 2026

Optimizing Functional-Domain Integrity of Circular Ribonucleic Acid With Improved Vaccine Immunogenicity by circDesign Algorithm.

circDesign is presented, an algorithm that explicitly incorporates IRES structural deviation into circRNA sequence design while jointly optimizing codon adaptation and thermodynamic stability and establishes IRES structural preservation as a mechanistic design principle for circRNA engineering and position circDesign a...

Congcong Xu, F. Jiang, Yifan Jiang et al. · Angewandte Chemie · 0 citations