PTEN restricts infectious bursal disease virus replication through modulating the AKT-TBK1-mediated type I IFN pathway
PTEN, a canonical dual-specificity tumor suppressor, plays a pivotal role in regulating diverse physiological and pathological processes, including cell proliferation, apoptosis, and immune responses. Infectious bursal disease virus (IBDV) causes an acute, severe immunosuppressive disease in chickens, inflicting catast...