Author

Zhiyao Zhuang

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Open access Aug 2026

MG2Act: A Mechanism-Inspired Sequential Attention Framework for Molecular Glue Degradation Prediction

This work presents MG2Act, a structure-independent framework that translates two-step logic into sequential cross-attention, using CRBN-mediated degradation as the most data-rich representative system.

Zhiyao Zhuang, Dan Teng, Xiao-Jing Xu et al. · bioRxiv · 0 citations