Integrating Network Toxicology and Untargeted Metabolomics to Identify Candidate Mechanisms and Metabolic Markers of α-Amanitin-Induced Hepatorenal Injury in Mice
Highlights What are the main findings? Metabolomic pathway analysis of plasma from α-amanitin-poisoned mice preliminarily reveals that plasma metabolites follow a temporally dynamic progression across seven different groups. PTGS2 emerges as a potential candidate target; propionylcarnitine and 2-arachidonoylglycerol (2...