Open access
Jul 2026
Integrating chemical priors and physical laws to mitigate hallucinations in structure-based drug design.
By merging chemical heuristics with physical laws, DrugRPG effectively addresses the hallucination crisis, shifting generative SBDD from scoring-oriented optimization toward high-fidelity, realistic lead discovery.
Zhongyu Liu, Yadong Liu, Yihang Zhou et al.
· Communications Chemistry · 0 citations