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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Zhi-Wen Luo

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Open access Aug 2026

Discovery of novel dual-target CDK12/PARP1 inhibitors for the treatment of triple-negative breast cancer.

The dual-target CDK12/PARP1 inhibitor 20b developed herein represents a novel lead molecule for TNBC drug development and exhibited markedly superior antiproliferative effects compared with single-target inhibitors and effectively reduced pSer2-CTD and PAR levels in TNBC cells.

Zhi-Jian Zhong, Miao Sun, Zhi-Wen Luo et al. · 0 citations
Conference Open access 2026

Latent Attention Denoising: A Training-Free Energy-Based Framework for Mitigating Hallucinations in Vision-Language Models

Latent Attention Denoising (LAD) is introduced, a principled and training-free framework that recasts attention calibration as a one-step score-based denoising process that achieves superior performance on both generative and discriminative tasks.

Zhiwen Luo, Siyu Jiang, Weilong Jiang et al. · 0 citations

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