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Author

Zhichao Qin

2 papers indexed here

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Open access Sep 2026

A microbiota-substrate-metabolite-target network suggests AKT1-associated links between gut microbiota-derived metabolites and osteoporosis.

OBJECTIVE To build a computational, hypothesis-generating framework that links gut microbiota-related metabolites with osteoporosis (OP) while retaining upstream microbial source and substrate information, and to prioritize candidate host targets, pathways, and modules for subsequent testing. METHODS Metabolites and...

Wen-Xing Zeng, Yuan Gong, Yi-Tao Liao et al. · 0 citations
Review Open access Aug 2026

Rewiring osteoimmune homeostasis in osteoporosis: T-cell subsets as key regulators and emerging therapeutic targets

Osteoporosis (OP) is a chronic metabolic bone disease characterized by reduced bone mass, microarchitectural deterioration, and an increased risk of fragility fractures. Although conventional views have emphasized the imbalance between osteoblasts and osteoclasts, advances in osteoimmunology have shown that T-cell subs...

Yuan Gong, Wen-Xing Zeng, Yi-Tao Liao et al. · 0 citations

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