Aug 2026
A Bioorthogonal Desilylation System Potentiates mRNA Therapeutics in Tumors.
This work presents a metabolically targeted, bioorthogonal-activated delivery strategy to address the selectivity and efficiency limitations of current mRNA medicines, providing a promising platform for precision oncology.
Mingzhe Zhang, Chunhong Wang, Xiaohan Xu et al.
· Journal of the American Chem... · 0 citations